SCHEMBL29178136

SCHEMBL29178136

O=S(=O)(C=Cc1cccc(Br)c1)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.51
HSD17B3 P37058 1/20 0.49
TLR9 Q9NR96 1/20 0.48
ALDH1A1 P00352 2/20 0.47
NFE2L2 Q16236 8/20 0.43
HSD11B1 P28845 1/20 0.42
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29178133 1.00 EGFR (0.51) EGFRHSD17B3TLR9ALDH1A1NFE2L2
SCHEMBL28410988 0.90 NFE2L2 (0.50) EGFRTLR9ALDH1A1NFE2L2
SCHEMBL28410987 0.90 NFE2L2 (0.50) EGFRTLR9ALDH1A1NFE2L2
SCHEMBL5572462 0.82 TLR9 (0.64) EGFRTLR9ALDH1A1NFE2L2
SCHEMBL29149692 0.82 TLR9 (0.64) EGFRTLR9ALDH1A1NFE2L2
SCHEMBL5572469 0.82 TLR9 (0.64) EGFRTLR9ALDH1A1NFE2L2
SCHEMBL1194075 0.81 TLR9 (0.53) EGFRTLR9ALDH1A1NFE2L2
SCHEMBL1194072 0.81 TLR9 (0.53) EGFRTLR9ALDH1A1NFE2L2
SCHEMBL7903214 0.80 CYP19A1 (0.59) EGFRTLR9ALDH1A1NFE2L2MAPT
SCHEMBL7903217 0.80 CYP19A1 (0.59) EGFRTLR9ALDH1A1NFE2L2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430125-A Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve 常州大学 2024-01-23 CN disclosed