SCHEMBL29178152

SCHEMBL29178152

Cc1cccc(C=CS(=O)(=O)c2ccccc2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.55
PPARG P37231 2/20 0.54
TLR9 Q9NR96 2/20 0.48
ALOX5 P09917 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
FBP1 P09467 1/20 0.46
NFE2L2 Q16236 7/20 0.44
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
RELA Q04206 2/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
XBP1 P17861 1/20 0.42
NFKB1 P19838 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29178150 1.00 EGFR (0.55) EGFRPPARGTLR9ALOX5PTGS1
SCHEMBL29149692 0.82 TLR9 (0.64) EGFRPPARGTLR9NFE2L2ALDH1A1
SCHEMBL5572462 0.82 TLR9 (0.64) EGFRPPARGTLR9NFE2L2ALDH1A1
SCHEMBL5572469 0.82 TLR9 (0.64) EGFRPPARGTLR9NFE2L2ALDH1A1
SCHEMBL30987467 0.81 TLR9 (0.59) EGFRPPARGTLR9NFE2L2TP53
SCHEMBL29022441 0.81 TLR9 (0.59) EGFRPPARGTLR9NFE2L2TP53
SCHEMBL942513 0.81 TLR9 (0.64) EGFRPPARGTLR9NFE2L2TP53
SCHEMBL7905290 0.81 TLR9 (0.64) EGFRPPARGTLR9NFE2L2TP53
SCHEMBL7903214 0.80 CYP19A1 (0.59) EGFRTLR9NFE2L2TDP1NPC1
SCHEMBL7903217 0.80 CYP19A1 (0.59) EGFRTLR9NFE2L2TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430125-A Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve 常州大学 2024-01-23 CN disclosed