SCHEMBL7905290

SCHEMBL7905290

Cc1ccc(S(=O)(=O)/C=C/c2ccccc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 2/20 0.64
PPARG P37231 3/20 0.58
ALDH1A1 P00352 5/20 0.51
MAPT P10636 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
NPC1 O15118 1/20 0.51
NFKB1 P19838 1/20 0.51
S100A4 P26447 1/20 0.51
MTOR P42345 1/20 0.51
RAB9A P51151 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
TP53 P04637 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
HPGD P15428 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL942513 1.00 TLR9 (0.64) TLR9PPARGALDH1A1MAPTTDP1
SCHEMBL29022441 0.93 TLR9 (0.59) TLR9PPARGALDH1A1MAPTTDP1
SCHEMBL30987467 0.93 TLR9 (0.59) TLR9PPARGALDH1A1MAPTTDP1
SCHEMBL28343916 0.90 TLR9 (0.72) TLR9PPARGALDH1A1MAPTTDP1
SCHEMBL5572462 0.86 TLR9 (0.64) TLR9PPARGALDH1A1KMT2ACYP1A2
SCHEMBL5572469 0.86 TLR9 (0.64) TLR9PPARGALDH1A1KMT2ACYP1A2
SCHEMBL29149692 0.86 TLR9 (0.64) TLR9PPARGALDH1A1KMT2ACYP1A2
SCHEMBL15497047 0.82 TLR9 (0.60) TLR9ALDH1A1MAPTTDP1MEN1
SCHEMBL16828395 0.82 NFE2L2 (0.60) TLR9ALDH1A1MAPTTDP1MEN1
SCHEMBL1195502 0.82 TLR9 (0.60) TLR9ALDH1A1MAPTTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430125-B Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve 常州大学 2025-03-21 CN disclosed
CN-117430125-A Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve 常州大学 2024-01-23 CN disclosed
US-6201131-B1 REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-13 US disclosed
US-5430177-A Polyfunctional Michael addition products ALBEMARLE CORPORATION (US) 1995-07-04 US disclosed
WO-1995014650-A1 MICHAEL REACTION ALBEMARLE CORPORATION (US) 1995-06-01 WO disclosed
EP-0618956-A1 POLYFUNCTIONAL MICHAEL ADDITION PRODUCTS AND REFRIGERATION COMPOSITIONS CONTAINING SUCH PRODUCTS ALBEMARLE CORPORATION (US) 1994-10-12 EP disclosed
US-5350875-A Michael reaction ALBEMARLE CORPORATION (US) 1994-09-27 US disclosed
WO-1993013188-A1 POLYFUNCTIONAL MICHAEL ADDITION PRODUCTS AND REFRIGERATION COMPOSITIONS CONTAINING SUCH PRODUCTS ETHYL CORPORATION (US) 1993-07-08 WO disclosed