Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26758591 | 0.88 | MAPT (0.84) | MAPTALDH1A1SMN1; SMN2POLBTP53 | |
| SCHEMBL28813844 | 0.85 | GAA (0.85) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29178277 | 0.84 | MAPT (0.62) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22601218 | 0.83 | MAPT (0.76) | MAPTALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL12240580 | 0.82 | SIRT6 (0.74) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26758590 | 0.82 | CA12 (0.78) | MAPTALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL29178284 | 0.82 | CA12 (0.78) | MAPTALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL14574146 | 0.81 | GAA (0.74) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12994627 | 0.81 | CA12 (0.76) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL26706248 | 0.81 | NPC1 (0.71) | MAPTALDH1A1SMN1; SMN2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736163-A | Phenylpiperazine derivative or pharmaceutical salt thereof, preparation method and application thereof in preparation of pain treatment drugs | 郑州大学第一附属医院 | 2024-03-22 | — | — | CN | claimed |
| CN-117736163-A | Phenylpiperazine derivative or pharmaceutical salt thereof, preparation method and application thereof in preparation of pain treatment drugs | 郑州大学第一附属医院 | 2024-03-22 | — | — | CN | disclosed |