Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PLEC | Q15149 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8608375 | 0.86 | POLB (0.46) | ALDH1A1KDM4EHDAC1ABL1POLB | |
| SCHEMBL5841965 | 0.82 | MRGPRX4 (0.54) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL17597118 | 0.81 | HDAC1 (0.44) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL30806171 | 0.81 | POLB (0.51) | ALDH1A1HPGDMAPTHTTPOLB | |
| SCHEMBL30983771 | 0.79 | GAA (0.71) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL2475653 | 0.79 | KDM4E (0.58) | ALDH1A1KDM4ESMN1; SMN2HSD17B10TSHR | |
| SCHEMBL29210718 | 0.79 | GAA (0.71) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL18182713 | 0.79 | AAK1 (0.48) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL5422597 | 0.79 | PTGDR2 (0.56) | ALDH1A1KDM4EHPGDMAP4K4NPSR1 | |
| SCHEMBL6542412 | 0.79 | MEN1 (0.58) | ALDH1A1MAPTPOLBTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561058-A | CDK2 inhibitors and methods of use thereof | 塞迪拉治疗股份有限公司 | 2024-02-13 | — | — | CN | disclosed |