Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542412 | 0.85 | MEN1 (0.58) | TDP1TSHRL3MBTL1MAPTALDH1A1 | |
| SCHEMBL978528 | 0.84 | HPGD (0.53) | MRGPRX4TDP1TSHRNPC1RAB9A | |
| SCHEMBL6321530 | 0.84 | MRGPRX4 (0.49) | MRGPRX4NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL30806171 | 0.84 | POLB (0.51) | TDP1TSHRNPC1RAB9AUSP2 | |
| SCHEMBL17513470 | 0.82 | TDP1 (0.54) | MRGPRX4TDP1NPC1RAB9AL3MBTL1 | |
| SCHEMBL2475653 | 0.82 | KDM4E (0.58) | TSHRKDM4ECASP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29178347 | 0.82 | ALDH1A1 (0.45) | TDP1TSHRNPC1RAB9AKDM4E | |
| SCHEMBL19707579 | 0.82 | MRGPRX4 (0.58) | MRGPRX4TDP1NPC1RAB9AL3MBTL1 | |
| SCHEMBL1930501 | 0.81 | CA2 (0.57) | MRGPRX4TDP1TSHRRAB9AKDM4E | |
| SCHEMBL3620365 | 0.80 | ALDH1A1 (0.49) | TDP1TSHRKDM4ENPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4946761-A | POLYMER CONTAINING CARBOXYL END GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-07 | — | — | US | claimed |
| US-7109243-B2 | Inhibitors of cathepsin S | IRM LLC (BM) | 2006-09-19 | — | — | US | disclosed |
| US-20060111357-A1 | Quinoline compounds for use in mch receptor related disorders | 7TM PHARMA A/S (DK) | 2006-05-25 | — | — | US | disclosed |
| US-6949658-B2 | Process for producing optically active α-amino acid and optically active α-amino acid amide | MITSUBISHI RAYON CO., LTD. (JP) | 2005-09-27 | — | — | US | disclosed |
| EP-1572212-A2 | QUINOLINE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM Pharma A/S (DK) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |
| US-20040198780-A1 | Inhibitors of cathepsin S | IRM LLC (BM) | 2004-10-07 | — | — | US | disclosed |
| WO-2004052370-A2 | QUINOLINE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2004-06-24 | — | — | WO | disclosed |
| US-20030171597-A1 | Process for producing optically active alpha-amino acid and optically active alpha-amino acid amine | MITSUBISHI RAYON CO., LTD. (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1300392-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-AMINO ACID AND OPTICALLY ACTIVE ALPHA-AMINO ACID AMIDE | Mitsubishi Rayon Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |
| EP-0458485-B1 | Image forming layer | FUJI PHOTO FILM CO LTD (JP) | 1998-07-29 | — | — | EP | disclosed |
| US-5395733-A | Unsaturated polymer layer that can be decarboxylated on exposure to light and sensitizers | FUJI PHOTO FILM CO., LTD. (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0458485-A2 | Image forming layer | Fuji Photo Film Co., Ltd. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4946761-A | POLYMER CONTAINING CARBOXYL END GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| US-4405705-A | HYDROPHILIC | TOYO BOSEKI KABUSHIKI KAISHA T/A TOYOBA CO., LTD. (JP) | 1983-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171597-A1 | Process for producing optically active alpha-amino acid and optically active alpha-amino acid amine | AADAT, BCAT1, BCAT2 | MRGPRX4 4539/4885TDP1 4133/4885TSHR 2744/4885 |
| US-20060111357-A1 | Quinoline compounds for use in mch receptor related disorders | MCHR2, MCHR1, MC1R | MRGPRX4 74/4885TDP1 3958/4885TSHR 80/4885 |
| US-20040198780-A1 | Inhibitors of cathepsin S | CTSS, CTSK, CTSE | MRGPRX4 1424/4885TDP1 3154/4885TSHR 4373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.