Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.57 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | STS | P08842 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351383 | 0.87 | PLA2G2A (0.64) | HSD17B3PLA2G2APLA2G5FFAR1ELANE | |
| SCHEMBL29178478 | 0.87 | PLA2G2A (0.64) | HSD17B3PLA2G2APLA2G5FFAR1ELANE | |
| SCHEMBL23043728 | 0.87 | PLA2G2A (0.64) | HSD17B3PLA2G2APLA2G5FFAR1ELANE | |
| SCHEMBL29178450 | 0.84 | HSD17B3 (0.57) | HSD17B3PLA2G2APLA2G5FFAR1ELANE | |
| SCHEMBL14900694 | 0.81 | HSD17B3 (0.68) | HSD17B3PLA2G2APLA2G5FFAR1HTT | |
| SCHEMBL5570402 | 0.81 | HSD17B3 (0.58) | HSD17B3PLA2G2APLA2G5FFAR1HTT | |
| SCHEMBL27318923 | 0.81 | HSD17B3 (0.63) | HSD17B3PLA2G2APLA2G5FFAR1ELANE | |
| SCHEMBL10489570 | 0.81 | HSD17B3 (0.67) | HSD17B3PLA2G2APLA2G5FFAR1HTT | |
| SCHEMBL5677489 | 0.81 | HSD17B3 (0.67) | HSD17B3PLA2G2APLA2G5FFAR1HTT | |
| SCHEMBL10353159 | 0.81 | HSD17B3 (0.67) | HSD17B3PLA2G2APLA2G5FFAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736081-A | Preparation method of polysubstituted phenyl Nur77 receptor modulator and application of polysubstituted phenyl Nur77 receptor modulator in anti-fibrosis aspect | 厦门大学 | 2024-03-22 | — | — | CN | disclosed |