Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 6/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178636 | 0.83 | KMT2A (0.34) | CA1CA9 | |
| SCHEMBL22787724 | 0.81 | AAK1 (0.39) | CA12CA1CA9PRMT5WDR77 | |
| SCHEMBL29494793 | 0.81 | AAK1 (0.39) | CA12CA1CA9PRMT5WDR77 | |
| SCHEMBL13035973 | 0.80 | CA12 (0.43) | CA12CA1CA9PRMT5WDR77 | |
| SCHEMBL31256429 | 0.79 | CA12 (0.38) | CA12CA1CA9PRMT5WDR77 | |
| SCHEMBL21318698 | 0.78 | AAK1 (0.46) | CA12CA1CA9PRMT5WDR77 | |
| SCHEMBL12072363 | 0.78 | CA12 (0.49) | CA12CA1CA9PRMT5WDR77 | |
| SCHEMBL31703038 | 0.77 | CXCR2 (0.36) | CA12CA1CA9PRMT5WDR77 | |
| SCHEMBL16042474 | 0.77 | CA12 (0.43) | CA12CA1CA9PRMT5WDR77 | |
| SCHEMBL13833256 | 0.77 | AAK1 (0.43) | CA12CA1CA9PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |