Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178896 | 0.88 | AURKA (0.40) | EGFRPOLBNR2F2ALDH1A1KDM4E | |
| SCHEMBL29178752 | 0.88 | AURKA (0.41) | FFAR1PPARDEGFRPOLBNR2F2 | |
| SCHEMBL29178748 | 0.84 | MDM2 (0.39) | FFAR1PPARD | |
| SCHEMBL29178641 | 0.83 | EGFR (0.41) | EGFRPOLBNR2F2ALDH1A1KDM4E | |
| SCHEMBL29178925 | 0.80 | PTGER1 (0.38) | FFAR1PPARDPPARA | |
| SCHEMBL29178926 | 0.79 | MDM2 (0.36) | FFAR1PPARD | |
| SCHEMBL29178883 | 0.78 | EGFR (0.48) | EGFRPOLBNR2F2ALDH1A1KDM4E | |
| SCHEMBL30739262 | 0.76 | MEN1 (0.38) | EGFRPOLBNR2F2ALDH1A1LMNA | |
| SCHEMBL29178709 | 0.75 | EGFR (0.40) | EGFRPOLBNR2F2ALDH1A1KDM4E | |
| SCHEMBL29178732 | 0.75 | AURKA (0.43) | EGFRPOLBNR2F2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |