Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL884909 | 1.00 | MET (0.83) | METINSR | |
| SCHEMBL886723 | 0.92 | MET (0.84) | METINSR | |
| SCHEMBL885070 | 0.91 | MET (1.00) | METINSR | |
| SCHEMBL885323 | 0.91 | MET (0.82) | METINSR | |
| SCHEMBL884973 | 0.90 | MET (0.83) | METINSR | |
| SCHEMBL886223 | 0.88 | MET (0.84) | METINSR | |
| SCHEMBL2063218 | 0.87 | MET (0.83) | METINSR | |
| SCHEMBL2914471 | 0.87 | MET (0.77) | METINSR | |
| SCHEMBL885077 | 0.87 | MET (0.85) | METINSR | |
| SCHEMBL885309 | 0.87 | MET (0.82) | METINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222647-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | Cephalon, Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2008051547-A1 | FUSED BICYCLIC DERIVATIVES OF 2,4-DIAMINOPYRIMIDINE AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2008-05-02 | — | — | WO | disclosed |