Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.60 |
| ▸ | PI4KB | Q9UBF8 | 13/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | PIK3C2G | O75747 | 2/20 | 0.50 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792221 | 0.90 | PI4KB (0.61) | PIK3CDPIK3CGPI4KBPIK3CAPIK3C2G | |
| SCHEMBL30792173 | 0.89 | PI4KB (0.60) | PIK3CDPIK3CGPI4KBPIK3CAPIK3C2G | |
| SCHEMBL48438 | 0.81 | PIK3CD (0.80) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB | |
| SCHEMBL29180114 | 0.80 | PI4KB (0.62) | PIK3CDPIK3CGPI4KBPIK3CAPIK3C2G | |
| SCHEMBL29180153 | 0.78 | PI4KB (0.53) | PIK3CDPIK3CGPI4KBPIK3C2G | |
| SCHEMBL29265081 | 0.78 | PIK3CD (0.66) | PIK3CDPIK3CGPI4KBPIK3CAPIK3C2G | |
| SCHEMBL14851648 | 0.77 | PI4KB (0.81) | PIK3CDPIK3CGPI4KBPIK3CAPIK3C2G | |
| SCHEMBL29180145 | 0.76 | PI4KB (0.52) | PIK3CDPIK3CGPI4KBPIK3C2G | |
| SCHEMBL48677 | 0.76 | PIK3CD (1.00) | PIK3CDPIK3CGPI4KBPIK3CAPIK3CB | |
| SCHEMBL22336672 | 0.76 | PIK3CD (0.83) | PIK3CDPIK3CGPI4KBPIK3CAPIK3C2G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534631-B | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117534631-A | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-117534631-B | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117534631-A | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |