Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.83 |
| ▸ | PI4KB | Q9UBF8 | 14/20 | 0.75 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.73 |
| ▸ | PIK3C2G | O75747 | 3/20 | 0.73 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24535632 | 0.89 | PIK3CD (0.78) | PIK3CDPI4KBPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL29265065 | 0.87 | PIK3CD (0.81) | PIK3CDPI4KBPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL22338451 | 0.86 | PIK3CD (0.74) | PIK3CDPI4KBPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL24535456 | 0.86 | PIK3CD (0.84) | PIK3CDPI4KBPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL22336563 | 0.86 | PI4KB (0.74) | PIK3CDPI4KBPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL22336531 | 0.85 | PIK3CD (0.85) | PIK3CDPI4KBPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL29265066 | 0.84 | PIK3CD (0.71) | PIK3CDPI4KBPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL24535575 | 0.84 | PIK3CD (0.86) | PIK3CDPI4KBPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL14851574 | 0.84 | PIK3CD (1.00) | PIK3CDPI4KBPIK3CGPIK3C2GPIK3CA | |
| SCHEMBL29420845 | 0.84 | PIK3CD (1.00) | PIK3CDPI4KBPIK3CGPIK3C2GPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163598-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |