SCHEMBL29180201

SCHEMBL29180201

CS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 14/20 0.54
CA1 P00915 13/20 0.50
MMP1 P03956 6/20 0.50
MMP2 P08253 6/20 0.50
MMP9 P14780 6/20 0.50
MMP8 P22894 6/20 0.50
MMP13 P45452 6/20 0.50
F2 P00734 4/20 0.45
PRSS1 P07477 4/20 0.45
PRSS2 P07478 4/20 0.45
PRSS3 P35030 4/20 0.45
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28034047 1.00 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL28034722 1.00 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL777456 0.97 CA2 (0.50) CA2CA1MMP1MMP2MMP9
SCHEMBL8719789 0.91 CA2 (0.42) CA2CA1MMP1MMP2MMP9
SCHEMBL776242 0.88 CA2 (0.40) CA2CA1MMP1MMP2MMP9
SCHEMBL16199284 0.88 CA2 (0.38) CA2CA1MMP1MMP2MMP9
SCHEMBL14827735 0.82 KDM4E (0.33) CA2CA1MMP1MMP2MMP9
SCHEMBL9335744 0.77 CA2 (0.59) CA2CA1MMP1MMP2MMP9
SCHEMBL24359009 0.76 CA2 (0.31) CA2CA1MMP1MMP2MMP9
SCHEMBL14040496 0.76 CA1 (0.43) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114730149-B Electrophotographic member, process cartridge, and electrophotographic image forming apparatus 佳能株式会社 2024-01-26 CN disclosed