Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26607921 | 0.86 | ABCB1 (0.47) | ABCG2ABCB1ABCC1BCHECNR2 | |
| SCHEMBL21801256 | 0.86 | KDM4E (0.50) | ABCG2ABCB1ABCC1BCHECNR2 | |
| SCHEMBL21801307 | 0.78 | CYP1A1 (0.60) | ABCG2ABCB1ABCC1MAOB | |
| SCHEMBL30744123 | 0.78 | CYP1A1 (0.60) | ABCG2ABCB1ABCC1MAOB | |
| SCHEMBL21801234 | 0.78 | HDAC3 (0.40) | ABCG2ABCB1ABCC1BCHEHDAC3 | |
| SCHEMBL30744124 | 0.78 | HDAC3 (0.40) | ABCG2ABCB1ABCC1BCHEHDAC3 | |
| SCHEMBL21801175 | 0.74 | TERT (0.62) | BCHEMAOAMAOB | |
| SCHEMBL30744111 | 0.74 | TERT (0.62) | BCHEMAOAMAOB | |
| SCHEMBL21801309 | 0.72 | ABCB1 (0.52) | ABCG2ABCB1ABCC1BCHECNR2 | |
| SCHEMBL21801150 | 0.71 | ABCB1 (0.56) | ABCG2ABCB1ABCC1BCHECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |