SCHEMBL29180263 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	NAMPT	P43490	2/20	0.37

▸	CYP2C9	P11712	1/20	0.37

▸	ROCK2	O75116	12/20	0.37

▸	LATS1	O95835	4/20	0.35

▸	LATS2	Q9NRM7	1/20	0.34

▸	TNF	P01375	1/20	0.34

▸	DYRK1A	Q13627	1/20	0.34

▸	ROCK1	Q13464	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23501364	0.93	ROCK2 (0.37)	NAMPTCYP2C9ROCK2LATS1LATS2
SCHEMBL23521642	0.91	ROCK2 (0.42)	NAMPTCYP2C9ROCK2LATS1TNF
SCHEMBL30744178	0.90	AAK1 (0.41)	NAMPTCYP2C9ROCK2LATS1TNF
SCHEMBL28580894	0.90	AAK1 (0.41)	NAMPTCYP2C9ROCK2LATS1TNF
SCHEMBL28409474	0.90	NAMPT (0.37)	NAMPTCYP2C9ROCK2LATS1LATS2
SCHEMBL23521448	0.90	ROCK2 (0.44)	NAMPTCYP2C9ROCK2TNFDYRK1A
SCHEMBL23927682	0.90	ROCK2 (0.44)	NAMPTCYP2C9ROCK2TNFDYRK1A
SCHEMBL28588721	0.88	ROCK2 (0.38)	NAMPTCYP2C9ROCK2TNFDYRK1A
SCHEMBL23501315	0.87	ROCK2 (0.37)	NAMPTCYP2C9ROCK2TNFDYRK1A
SCHEMBL23963658	0.86	ROCK2 (0.37)	NAMPTCYP2C9ROCK2TNFDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-112979675-B	Small molecular sulfur-containing heterocyclic compound	维眸生物科技（上海）有限公司	2023-12-19	—	—	CN	disclosed