Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 8/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916208 | 0.84 | GRM1 (0.52) | LMNASMN1; SMN2GRM1GRM4 | |
| SCHEMBL5418153 | 0.83 | LMNA (0.42) | LMNASMN1; SMN2GRM1GRM4TYMS | |
| SCHEMBL3374587 | 0.83 | ANPEP (0.46) | LMNASMN1; SMN2GRM1GRM4TYMS | |
| SCHEMBL5429466 | 0.83 | GRM1 (0.51) | LMNASMN1; SMN2GRM1GRM4 | |
| SCHEMBL2916938 | 0.81 | LMNA (0.40) | LMNASMN1; SMN2GRM1GRM4TYMS | |
| SCHEMBL3376357 | 0.78 | LMNA (0.47) | LMNASMN1; SMN2GRM1GRM4TYMS | |
| SCHEMBL3376337 | 0.77 | LMNA (0.46) | LMNASMN1; SMN2GRM1GRM4TYMS | |
| SCHEMBL3376240 | 0.76 | LMNA (0.45) | LMNASMN1; SMN2GRM1GRM4TYMS | |
| SCHEMBL14579468 | 0.74 | GRM1 (0.41) | LMNASMN1; SMN2GRM1GRM4MEN1 | |
| SCHEMBL12402290 | 0.74 | HPGD (0.35) | LMNASMN1; SMN2GRM1GRM4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006107-B1 | Phthalamide derivatives, or salt thereof agrohorticultural insecticide, and method for using the same | NIHON NOHYAKU CO LTD (JP) | 2010-09-01 | — | — | EP | disclosed |
| US-6603044-B1 | The present invention provides a phthalamide derivative of the formula (I): agrohorticultural insecticide containing said compound as active ingredient and exhibiting an excellent insecticidal effect. | NIHON NOHYAKU CO., LTD. (JP) | 2003-08-05 | — | — | US | disclosed |
| EP-1006107-A2 | Phthalamide derivatives, or salt thereof agrohorticultural insecticide, and method for using the same | NIHON NOHYAKU CO., LTD. (JP) | 2000-06-07 | — | — | EP | disclosed |