Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29181533 | 0.94 | DHODH (0.37) | DHODHTRPA1POLBKDM4EMAPT | |
| SCHEMBL29181527 | 0.93 | DHODH (0.38) | DHODHTRPA1POLBKDM4EMAPT | |
| SCHEMBL29181548 | 0.93 | DHODH (0.38) | DHODHTRPA1POLBKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL29181557 | 0.92 | DHODH (0.37) | DHODHTRPA1POLBKDM4EMAPT | |
| SCHEMBL29181519 | 0.89 | DHODH (0.37) | DHODHTRPA1AVPR1AHSD11B1MALT1 | |
| SCHEMBL29181552 | 0.88 | DHODH (0.37) | DHODHTRPA1HSD11B1MALT1 | |
| SCHEMBL29181526 | 0.87 | DHODH (0.36) | DHODHTRPA1KDM4ENPSR1AVPR1A | |
| SCHEMBL29181516 | 0.86 | DHODH (0.37) | DHODHTRPA1POLBKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL29181536 | 0.85 | DHODH (0.37) | DHODHTRPA1POLBKDM4EMAPT | |
| SCHEMBL29181596 | 0.85 | DHODH (0.38) | DHODHTRPA1POLBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | disclosed |