SCHEMBL29181737

SCHEMBL29181737

O=C1C=Cc2cc(O)c(Br)cc2C1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
HSP90AA1 P07900 1/20 0.35
GPR35 Q9HC97 1/20 0.33
CISD1 Q9NZ45 1/20 0.31
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18403857 0.84 GSK3A (0.43) GSK3AGSK3B
SCHEMBL6230840 0.77 GSK3A (0.50) GSK3AGSK3B
SCHEMBL28510714 0.74 GSK3A (0.48) GSK3AGSK3B
SCHEMBL5479958 0.74 GSK3A (0.48) GSK3AGSK3B
SCHEMBL15353713 0.71 PTPRC (0.44) GSK3AGSK3B
SCHEMBL28642002 0.71 CMA1 (0.43) GSK3AGSK3BHSP90AA1ALOX15
SCHEMBL8086692 0.71 TYR (0.41) GSK3AGSK3B
SCHEMBL4709430 0.68 MEN1 (0.42) GSK3AGSK3BHSP90AA1ALOX15
SCHEMBL14251165 0.65 MEN1 (0.39) GSK3AGSK3BHSP90AA1ALOX15
SCHEMBL29369493 0.65 ACHE (0.42) GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117487150-A Polycarbonate, preparation method and application thereof 万华化学集团股份有限公司 2024-02-02 CN disclosed