SCHEMBL29181772

SCHEMBL29181772

CN(C1CCNCC1)S(=O)(=O)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA3 P07451 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA13 Q8N1Q1 1/20 0.53
CA14 Q9ULX7 1/20 0.53
CA5B Q9Y2D0 1/20 0.53
SLC6A2 P23975 1/20 0.49
SLC6A4 P31645 1/20 0.49
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HTR2A P28223 11/20 0.46
HTR2C P28335 11/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14538240 0.82 HTR2A (0.66) SLC6A2SLC6A4ALDH1A1KDM4EMEN1
SCHEMBL29181773 0.81 HTR2A (0.67) CA12CA1CA2CA3CA4
SCHEMBL3485687 0.80 ALDH1A1 (0.71) SLC6A2SLC6A4ALDH1A1KDM4EMEN1
Hydrochloric Acid SCHEMBL27714396 0.79 ALDH1A1 (0.69) SLC6A2SLC6A4ALDH1A1KDM4EMEN1
SCHEMBL29181762 0.78 HTR2C (0.68) SLC6A2SLC6A4ALDH1A1KDM4EMEN1
SCHEMBL29181745 0.78 HTR2A (0.68) SLC6A2SLC6A4ALDH1A1KDM4EMEN1
SCHEMBL22084761 0.78 CA12 (0.50) CA12CA1CA2CA3CA4
SCHEMBL22084763 0.78 CA12 (0.50) CA12CA1CA2CA3CA4
SCHEMBL27178860 0.78 MAPT (0.44) CA12CA1CA2CA3CA4
SCHEMBL2108242 0.77 KMT2A (0.50) CA1CA2SLC6A2SLC6A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117645567-A Chalcone derivative containing piperidine sulfonamide structure, and preparation method and application thereof 贵州大学 2024-03-05 CN disclosed