Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.42 |
| ▸ | GABRP | O00591 | 6/20 | 0.42 |
| ▸ | GABRD | O14764 | 6/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.42 |
| ▸ | GABRE | P78334 | 6/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24955122 | 0.84 | MAPK1 (0.53) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2410433 | 0.81 | KDM4E (0.51) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL22919996 | 0.77 | KMT2A (0.45) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL31172628 | 0.77 | CYP1A2 (0.55) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL82426 | 0.77 | CYP1A2 (0.55) | CYP1A2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30630825 | 0.76 | EGLN1 (0.40) | LMNAPIK3CA | |
| SCHEMBL20176923 | 0.76 | EGLN1 (0.40) | LMNAPIK3CA | |
| SCHEMBL4018291 | 0.76 | ACR (0.52) | POLBALDH1A1LMNANPC1MAPT | |
| SCHEMBL23724971 | 0.76 | CNR1 (0.34) | POLBKDM4ESMN1; SMN2CNR2 | |
| SCHEMBL4014047 | 0.75 | CA1 (0.55) | ALDH1A1LMNANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813090-A | Methods and compositions for targeting PD-L1 | 安力高医药股份有限公司 | 2024-04-02 | — | — | CN | disclosed |