⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154493 | 0.92 | PTPN7 (0.46) | — | |
| SCHEMBL3856077 | 0.89 | PTPN7 (0.50) | — | |
| SCHEMBL4431565 | 0.89 | PTPN7 (0.50) | — | |
| SCHEMBL158129 | 0.89 | PTPN7 (0.50) | — | |
| SCHEMBL10948772 | 0.89 | PTPN7 (0.50) | — | |
| SCHEMBL7991151 | 0.89 | PTPN7 (0.50) | — | |
| SCHEMBL3858612 | 0.89 | PTPN7 (0.50) | — | |
| SCHEMBL10948997 | 0.89 | PTPN7 (0.50) | — | |
| SCHEMBL3863172 | 0.89 | PTPN7 (0.50) | — | |
| SCHEMBL1117071 | 0.88 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120232105-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING OSTEOCLAST GROWTH | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-09-13 | — | — | US | claimed |
| US-12037439-B2 | Water-based polymer hydrogel system | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-07-16 | — | — | US | disclosed |
| EP-3191484-B1 | PYRAZOLOPYRIDINE DERIVATIVES AND THEIR USE IN THERAPY | HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) | 2024-06-12 | — | — | EP | disclosed |
| WO-2024119098-A1 | LIPID NANOPARTICLE (LNP) DELIVERY SYSTEMS AND FORMULATIONS | PRIME MEDICINE, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| EP-4351553-A1 | NOVEL ANTI-FIBROTIC DRUGS | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH (DE) | 2024-04-17 | — | — | EP | disclosed |
| CN-117642185-A | Improved CD30 targeting antibody drug conjugates and uses thereof | 路德维希-马克西米利安慕尼黑大学 | 2024-03-01 | — | — | CN | disclosed |
| US-20240018281-A1 | WATER-BASED POLYMER HYDROGEL SYSTEM | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-01-18 | — | — | US | disclosed |
| US-20240018282-A1 | METHOD FOR MAKING AN AQUEOUS HYDROGEL COMPOSITION | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2024-01-18 | — | — | US | disclosed |
| US-11814459-B2 | Aqueous solution method for forming a hydrogel composition | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2023-11-14 | — | — | US | disclosed |
| US-20230348453-A1 | HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF | IOMX THERAPEUTICS AG (DE) | 2023-11-02 | — | — | US | disclosed |
| US-4996201-A | Alzheimer's disease | WARNER-LAMBERT CO. (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0411616-A1 | 4-(N-substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof as centrally acting muscarinic agents | WARNER-LAMBERT COMPANY (US) | 1991-02-06 | — | — | EP | disclosed |
| EP-0411615-A1 | 4-(N-substituted amino)-2-butynyl-1-ureas and thioureas and derivatives thereof as centrally acting muscarinic agents | WARNER-LAMBERT COMPANY (US) | 1991-02-06 | — | — | EP | disclosed |
| US-4988688-A | Cognitive activators | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0232776-B1 | 2,5,6,7-TETRANOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1990-10-24 | — | — | EP | disclosed |
| EP-0389162-A1 | 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1990-09-26 | — | — | EP | disclosed |
| US-4880939-A | ANTISECRETORY AGENTS, HYPOTENSIVES, ANTICOAGULANTS | TORAY INDUSTRIES (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4775692-A | ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT | TORAY INDUSTRIES, INC. (JP) | 1988-10-04 | — | — | US | disclosed |
| EP-0274064-A2 | 2,5,6,7-Tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1988-07-13 | — | — | EP | disclosed |
| EP-0232776-A2 | 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1987-08-19 | — | — | EP | disclosed |