Sugi Predict

Sugi Predict / Compounds / SCHEMBL158129

SCHEMBL158129

SCHEMBL158129

[CH2]CCC#CCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN7 P35236 5/20 0.50
▸ HMGCR P04035 3/20 0.50
▸ RECQL P46063 2/20 0.45
▸ TDP1 Q9NUW8 2/20 0.45
▸ TSHR P16473 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ USP2 O75604 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ BLM P54132 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ MCL1 Q07820 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ EPHX2 P34913 3/20 0.39
▸ RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7991151 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL10948997 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL4431565 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3863172 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3858612 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL3856077 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL10948772 1.00 PTPN7 (0.50) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL154493 0.97 PTPN7 (0.46) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL10900975 0.90 PTPN7 (0.53) PTPN7HMGCRRECQLTDP1TSHR
SCHEMBL14759549 0.90 HMGCR (0.53) PTPN7HMGCRRECQLTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1284 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024511-B2 Substituted imidazo[1,2-a]pyridin-2-ylamine compounds, and pharmaceutical compositions and methods of use thereof SHANGHAI FUDAN-ZHANGJIANG BIO-PHARMACEUTICAL CO., LTD. (CN) 2024-07-02 — — US disclosed
US-20240208927-A1 WNT SIGNALING PATHWAY INHIBITORS FOR TREATMENTS OF DISEASE UNIVERSITY OF MARYLAND, BALTIMORE 2024-06-27 — — US disclosed
EP-4385574-A2 ANDROGEN RECEPTOR MODULATOR FOR THE TREATMENT OF PROSTATE CANCER AND ANDROGEN RECEPTOR-ASSOCIATED DISEASES The Regents of the University of California (US) 2024-06-19 — — EP disclosed
US-20240183035-A1 AREA SELECTIVE DEPOSITION THROUGH SURFACE SILYLATION APPLIED MATERIALS, INC. (US) 2024-06-06 — — US disclosed
US-20240174635-A1 TLR 9 INHIBITORS INSILICO MEDICINE IP LIMITED (HK) 2024-05-30 — — US disclosed
WO-2024112550-A1 AREA SELECTIVE DEPOSITION THROUGH SURFACE SILYLATION APPLIED MATERIALS, INC. (US) 2024-05-30 — — WO disclosed
US-11972940-B2 Area selective carbon-based film deposition APPLIED MATERIALS, INC. (US) 2024-04-30 — — US disclosed
US-11970777-B2 Deposition of low-k films APPLIED MATERIALS, INC. (US) 2024-04-30 — — US disclosed
US-20240132452-A1 DIARYLHYDANTOIN COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-25 — — US disclosed
EP-4346811-A1 DUAL WNT SIGNALING PATHWAY INHIBITORS AND AMPK ACTIVATORS FOR TREATMENTS OF DISEASE University of Maryland, Baltimore (US) 2024-04-10 — — EP disclosed
US-4647585-A Bicycloheptane substituted ethers E. R. SQUIBB & SONS, INC. (US) 1987-03-03 — — US disclosed
US-4647573-A 7-oxabicycloheptane substituted thioamide-amide prostaglandin analogs E. R. SQUIBB & SONS, INC. (US) 1987-03-03 — — US disclosed
EP-0210664-A2 7-oxabicycloheptane substituted diacid diamide prostaglandin analogs E.R. Squibb & Sons, Inc. (US) 1987-02-04 — — EP disclosed
US-4638012-A 7-oxabicycloheptane α-substituted ketone prostaglandin analogs useful in the treatment of thrombotic disease E. R. SQUIBB & SONS, INC. (US) 1987-01-20 — — US disclosed
EP-0207684-A2 7-Oxabicycloheptane substituted diamide and its congener prostaglandin analogs E.R. Squibb & Sons, Inc. (US) 1987-01-07 — — EP disclosed
EP-0205834-A1 7-Thiabicycloheptane substituted ethers E.R. Squibb & Sons, Inc. (US) 1986-12-30 — — EP disclosed
US-4611007-A 7-oxabicycloheptane substituted prostaglandin analogs useful in the treatment of thrombotic disease E. R. SQUIBB & SONS, INC. (US) 1986-09-09 — — US disclosed
US-4611006-A 5,6-epoxy-7-oxabicycloheptane substituted ethers useful in the treatment of thrombotic disease E. R. SQUIBB & SONS, INC. (US) 1986-09-09 — — US disclosed
US-4608386-A ASTHMA E. R. SQUIBB & SONS, INC. (US) 1986-08-26 — — US disclosed
US-4595692-A 7-thiabicycloheptane substituted ethers E. R. SQUIBB & SONS, INC. (US) 1986-06-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132452-A1 DIARYLHYDANTOIN COMPOUNDS BPHL, AR, SHBG PTPN7 4133/4885HMGCR 837/4885RECQL 1763/4885
US-12024511-B2 Substituted imidazo[1,2-a]pyridin-2-ylamine compounds, and pharmaceutical compositions and methods of use thereof JAK1, JAK2, JAK3 PTPN7 479/4885HMGCR 1453/4885RECQL 1301/4885
US-20240208927-A1 WNT SIGNALING PATHWAY INHIBITORS FOR TREATMENTS OF DISEASE WNT1, CTNNB1, WNT3A PTPN7 1478/4885HMGCR 869/4885RECQL 4078/4885
US-20240174635-A1 TLR 9 INHIBITORS TLR9, TLR1, TLR7 PTPN7 135/4885HMGCR 3854/4885RECQL 3952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.