Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PAM | P19021 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658855 | 1.00 | DGKA (0.57) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL3823631 | 1.00 | DGKA (0.57) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL9768598 | 1.00 | DGKA (0.57) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL3662225 | 1.00 | DGKA (0.57) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL5732818 | 1.00 | DGKA (0.57) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL7771101 | 1.00 | DGKA (0.57) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL3121472 | 1.00 | DGKA (0.57) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL9985650 | 1.00 | DGKA (0.57) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL62214 | 1.00 | DGKA (0.57) | DGKALMNAPAMCES2CES1 | |
| SCHEMBL1510009 | 1.00 | DGKA (0.57) | DGKALMNAPAMCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | claimed |
| CN-117396477-A | Pyridyl-substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-01-12 | — | — | CN | claimed |
| CN-111194215-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2020-05-22 | — | — | CN | claimed |
| CN-107519931-B | The preparation method of immobilized 9 azabicyclic [3.3.1] nonyl, 9 oxygen radical of crosslinked polystyrene microsphere | 深圳市宏辉浩医药科技有限公司 | 2018-04-17 | — | — | CN | claimed |
| CN-107519931-A | The preparation method of the immobilized oxygen radical of 9 azabicyclic [3,3,1] nonyl 9 of crosslinked polystyrene microsphere | 深圳市宏辉浩医药科技有限公司 | 2017-12-29 | — | — | CN | claimed |
| CN-104093725-B | Mixtures of diphosphinic acids and alkylphosphinic acids, method for the production thereof, and use thereof | 科莱恩金融(BVI)有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-103068766-B | There is acrylic artificial marble and the manufacture method thereof of granite pattern | 乐金华奥斯株式会社 | 2016-10-05 | — | — | CN | claimed |
| CN-103189327-B | Acrylic acid synthetic marble with pearl-containing pattern and preparation method thereof | 乐金华奥斯株式会社 | 2016-08-24 | — | — | CN | claimed |
| CN-103827120-A | 6H-thieno [3,2-f ] [1,2,4] triazolo [4,3-a ] [1,4] diazepine | BAYER IP GMBH | 2014-05-28 | — | — | CN | claimed |
| US-20070287688-A1 | Pharmaceutical Compositions for Topical Application | MACRO CHEM CORPORATION | 2007-12-13 | — | — | US | claimed |
| EP-1648364-A2 | PHARMACEUTICAL COMPOSITIONS FOR TOPICAL APPLICATION | MacroChem Corporation (US) | 2006-04-26 | — | — | EP | claimed |
| WO-2005007100-A2 | PHARMACEUTICAL COMPOSITIONS FOR TOPICAL APPLICATION | MACROCHEM CORPORATION (US) | 2005-01-27 | — | — | WO | claimed |
| CN-119320388-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2025-01-17 | — | — | CN | disclosed |
| US-20240277668-A1 | HISTAMINE RECEPTOR AGONISTS FOR CANCER THERAPY IN CANCER PATIENTS UNRESPONSIVE TO CANCER IMMUNOTHERAPY AND WITH ELEVATED MYELOID DERIVED SUPPRESSOR CELLS | TSP THERAPEUTICS INC. | 2024-08-22 | — | — | US | disclosed |
| CN-118344370-A | Isoindolinone and indazole compounds for EGFR degradation | C4医药公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| EP-0711813-A2 | Coating varnish composition and antifouling coating composition | Hitachi Chemical Co., Ltd. (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5407943-A | Azaspiro quinolone antibacterial agents | PFIZER INC. (US) | 1995-04-18 | — | — | US | disclosed |
| EP-0326737-B1 | COPPER POWDER FOR ELECTROCONDUCTIVE PAINTS AND ELECTROCONDUCTIVE PAINT COMPOSITIONS | MITSUI KINZOKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-08 | — | — | EP | disclosed |
| EP-0326737-A2 | Copper powder for electroconductive paints and electroconductive paint compositions | MITSUI KINZOKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287688-A1 | Pharmaceutical Compositions for Topical Application | CYP8B1, NR1H3, NR1H2 | DGKA 2030/4885LMNA 1726/4885PAM 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.