Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.49 |
| ▸ | SKP1 | P63208 | 2/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | GALR1 | P47211 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15047026 | 0.81 | CKS1B (0.56) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL21796663 | 0.80 | GPR119 (0.56) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL18551087 | 0.80 | GPR119 (0.54) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL29182760 | 0.79 | HRH4 (0.45) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL24851455 | 0.79 | CKS1B (0.53) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL31383499 | 0.79 | CKS1B (0.48) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL21796860 | 0.78 | CKS1B (0.47) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL26924817 | 0.78 | GPR119 (0.50) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL16333288 | 0.78 | CKS1B (0.53) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL20142337 | 0.77 | CKS1B (0.59) | CKS1BSKP1SKP2MAP4K4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351560-A1 | ANTICANCER COMPOUNDS | The Regents of the University of California (US) | 2024-04-17 | — | — | EP | disclosed |
| CN-117794525-A | Anticancer compounds | 加利福尼亚大学董事会 | 2024-03-29 | — | — | CN | disclosed |
| WO-2022261204-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-15 | — | — | WO | disclosed |