SCHEMBL29183282

SCHEMBL29183282

CCCCCCCNS(=O)(=O)c1ccc(OC)cc1

nearest known ligand 0.88

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.84
PKM P14618 1/20 0.84
LMNA P02545 2/20 0.68
HTT P42858 2/20 0.68
MAPK1 P28482 1/20 0.68
USP2 O75604 1/20 0.68
MEN1 O00255 2/20 0.64
KMT2A Q03164 2/20 0.64
SMN1; SMN2 Q16637 2/20 0.63
HSD17B10 Q99714 1/20 0.59
POLB P06746 1/20 0.58
TSHR P16473 1/20 0.56
HTR7 P34969 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29183292 1.00 ALDH1A1 (0.84) ALDH1A1PKMLMNAHTTMAPK1
SCHEMBL9149721 1.00 ALDH1A1 (0.84) ALDH1A1PKMLMNAHTTMAPK1
SCHEMBL29163150 1.00 ALDH1A1 (0.84) ALDH1A1PKMLMNAHTTMAPK1
SCHEMBL29207011 1.00 ALDH1A1 (0.84) ALDH1A1PKMLMNAHTTMAPK1
SCHEMBL1465523 0.98 ALDH1A1 (0.87) ALDH1A1PKMLMNAHTTMAPK1
SCHEMBL7185182 0.94 ALDH1A1 (0.84) ALDH1A1PKMLMNAHTTMAPK1
SCHEMBL5770948 0.87 ALDH1A1 (0.77) ALDH1A1PKMLMNAHTTUSP2
SCHEMBL29206992 0.86 ALDH1A1 (0.82) ALDH1A1PKMLMNAUSP2MEN1
SCHEMBL30826421 0.86 ALDH1A1 (0.82) ALDH1A1PKMLMNAHTTUSP2
SCHEMBL29206991 0.86 ALDH1A1 (0.82) ALDH1A1PKMLMNAUSP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117658945-A Synthesis method of persulfate-induced alkylation modified nitrogen heterocyclic compound 浙江工业大学 2024-03-08 CN disclosed
CN-116375611-A Method for synthesizing difluoroalkyl compound from fatty amine 浙江工业大学 2023-07-04 CN disclosed