SCHEMBL2918461

SCHEMBL2918461

CCCCCCCCCCc1ccccc1OS(=O)(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.56
THRB P10828 1/20 0.56
PPARA Q07869 3/20 0.50
LIPG Q9Y5X9 1/20 0.50
ALOX5 P09917 1/20 0.49
PTGS2 P35354 1/20 0.49
PPARG P37231 2/20 0.48
BID P55957 3/20 0.43
MCL1 Q07820 3/20 0.43
BCL2L1 Q07817 2/20 0.43
BAK1 Q16611 2/20 0.43
KAT8 Q9H7Z6 2/20 0.43
EP300 Q09472 1/20 0.43
KAT2A Q92830 1/20 0.43
KAT2B Q92831 1/20 0.43
KAT5 Q92993 1/20 0.43
SAE1 Q9UBE0 1/20 0.43
LTB4R Q15722 1/20 0.42
LTB4R2 Q9NPC1 1/20 0.42
ELANE P08246 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6028371 1.00 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL5028619 1.00 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL29240382 1.00 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL327172 1.00 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL28271334 1.00 THRA (0.56) THRATHRBPPARALIPGALOX5
SCHEMBL30408777 1.00 THRA (0.56) THRATHRBPPARALIPGALOX5
Ammonia Solution, Strong SCHEMBL10961216 0.98 THRA (0.55) THRATHRBPPARALIPGALOX5
SCHEMBL13505354 0.98 THRA (0.55) THRATHRBPPARALIPGALOX5
Ammonia Solution, Strong SCHEMBL9118739 0.98 THRA (0.55) THRATHRBPPARALIPGALOX5
SCHEMBL1589844 0.98 THRA (0.55) THRATHRBPPARALIPGALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1486193-B1 METHOD OF STABILIZING SILICONE OIL-CONTAINING COSMETIC COMPOSITION HAKUTO KK (JP) 2010-09-01 EP disclosed
EP-1500385-B1 METHOD OF FOAM STABILIZATION FOR FOAM COSMETIC HAKUTO KK (JP) 2008-06-25 EP disclosed
EP-1500385-A1 METHOD OF FOAM STABILIZATION FOR FOAM COSMETIC Hakuto Co., Ltd (JP) 2005-01-26 EP disclosed
EP-1486193-A1 METHOD OF STABILIZING SILICONE OIL-CONTAINING COSMETIC COMPOSITION Hakuto Co., Ltd (JP) 2004-12-15 EP disclosed