Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27220952 | 0.88 | ACHE (0.64) | ACHEEPHX2 | |
| SCHEMBL22400737 | 0.88 | ACHE (0.62) | ACHEEPHX2 | |
| SCHEMBL10927317 | 0.86 | ACHE (0.59) | ACHEEPHX2 | |
| SCHEMBL28871341 | 0.82 | ACHE (0.44) | ACHEEPHX2 | |
| SCHEMBL6250763 | 0.81 | ACHE (0.41) | ACHEEPHX2 | |
| SCHEMBL6250771 | 0.81 | ACHE (0.41) | ACHEEPHX2 | |
| SCHEMBL21404674 | 0.81 | ACHE (0.49) | ACHEEPHX2 | |
| SCHEMBL15698492 | 0.81 | ACHE (0.45) | ACHEEPHX2 | |
| SCHEMBL6252113 | 0.80 | EPHX2 (0.44) | ACHEEPHX2 | |
| SCHEMBL6252104 | 0.80 | EPHX2 (0.44) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714417-B1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LTD (GB) | 1998-06-10 | — | — | EP | claimed |
| EP-3558930-A1 | NEW PROCESS FOR EARLY SACUBITRIL INTERMEDIATES | Novartis AG (CH) | 2019-10-30 | — | — | EP | disclosed |
| EP-3481799-A1 | NEW PROCESS FOR EARLY SACUBITRIL INTERMEDIATES | Novartis AG (CH) | 2019-05-15 | — | — | EP | disclosed |
| WO-2018116203-A1 | NEW PROCESS FOR EARLY SACUBITRIL INTERMEDIATES | NOVARTIS AG (CH) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018007919-A1 | NEW PROCESS FOR EARLY SACUBITRIL INTERMEDIATES | NOVARTIS AG (CH) | 2018-01-11 | — | — | WO | disclosed |
| EP-2609071-A1 | NEW PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE MANUFACTURE NEP INHIBITORS | Novartis AG (CH) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012025502-A1 | NEW PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL FOR THE MANUFACTURE NEP INHIBITORS | NOVARTIS AG (CH) | 2012-03-01 | — | — | WO | disclosed |
| WO-2004074336-A1 | NOVEL CATIONIC COPOLYMERS, USE THEREOF FOR THE VECTORISATION OF BIOMOLECULES AND SYNTHETIC INTERMEDIATES FOR THE SAME | HALISOL (FR) | 2004-09-02 | — | — | WO | disclosed |
| EP-0714417-B1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LTD (GB) | 1998-06-10 | — | — | EP | disclosed |
| EP-0714417-A1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005408-A1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1995-02-23 | — | — | WO | disclosed |