Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9909941 | 0.86 | EGLN2 (0.44) | EGLN2MAPKAPK2GPR119CYP17A1TTK | |
| SCHEMBL1368674 | 0.85 | S1PR2 (0.58) | MAPKAPK2S1PR2BCHEACHECYP17A1 | |
| SCHEMBL9909940 | 0.80 | S1PR2 (0.47) | MAPKAPK2S1PR2BCHEACHECYP17A1 | |
| SCHEMBL30938620 | 0.79 | MAPKAPK2 (0.38) | EGLN2MAPKAPK2CYP17A1TTK | |
| SCHEMBL29529712 | 0.78 | EGLN2 (0.47) | EGLN2GPR119CYP17A1ATR | |
| SCHEMBL2961095 | 0.78 | EGLN2 (0.47) | EGLN2GPR119CYP17A1ATR | |
| SCHEMBL31226805 | 0.78 | EGLN2 (0.42) | EGLN2MAPKAPK2CYP17A1TTK | |
| SCHEMBL18016765 | 0.77 | S1PR2 (0.45) | MAPKAPK2S1PR2BCHEACHECYP17A1 | |
| SCHEMBL23608433 | 0.76 | SMARCA2 (0.44) | MAPKAPK2S1PR2BCHEACHESYK | |
| SCHEMBL29818315 | 0.76 | SMARCA2 (0.44) | MAPKAPK2S1PR2BCHEACHESYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486790-A | Preparation method of 4-amino-6-chloro-2-picolinic acid | 南通药明康德医药科技有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-117486790-A | Preparation method of 4-amino-6-chloro-2-picolinic acid | 南通药明康德医药科技有限公司 | 2024-02-02 | — | — | CN | disclosed |