Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29185132 | 0.79 | EGLN2 (0.44) | MAPKAPK2TTKEGLN2CYP17A1 | |
| SCHEMBL9909941 | 0.67 | EGLN2 (0.44) | MAPKAPK2TTKEGLN2CYP17A1 | |
| SCHEMBL17230177 | 0.66 | IDO1 (0.46) | — | |
| SCHEMBL24003976 | 0.66 | SYK (0.48) | CDK1EGFREGLN2JAK2JAK1 | |
| SCHEMBL1368674 | 0.66 | S1PR2 (0.58) | MAPKAPK2CYP17A1 | |
| SCHEMBL17230172 | 0.65 | KCNQ4 (0.47) | CYP17A1 | |
| SCHEMBL2961095 | 0.65 | EGLN2 (0.47) | AREGLN2JAK2JAK1CYP17A1 | |
| SCHEMBL3438586 | 0.65 | CA12 (0.44) | CYP17A1 | |
| SCHEMBL29529712 | 0.65 | EGLN2 (0.47) | AREGLN2JAK2JAK1CYP17A1 | |
| SCHEMBL6681859 | 0.64 | KMT2A (0.43) | MAPKAPK2AREGLN2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024151919-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2024-07-18 | — | — | WO | disclosed |