Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.63 |
| ▸ | TACR1 | P25103 | 3/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | KLK7 | P49862 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29186149 | 1.00 | SCN9A (0.63) | SCN9ATACR1PPARGKLK7ACE | |
| SCHEMBL22109027 | 0.91 | PPARG (0.62) | TACR1PPARGMEN1KMT2AMAPT | |
| SCHEMBL22108941 | 0.91 | PPARG (0.62) | TACR1PPARGMEN1KMT2AMAPT | |
| SCHEMBL27427419 | 0.89 | SCN9A (0.58) | SCN9ATACR1PPARGKLK7ACE | |
| SCHEMBL30961940 | 0.89 | SCN9A (0.58) | SCN9ATACR1PPARGKLK7ACE | |
| SCHEMBL1177004 | 0.86 | SCN9A (0.66) | SCN9ATACR1KLK7ACECTSL | |
| SCHEMBL31407830 | 0.85 | MEN1 (0.73) | SCN9ATACR1PPARGKLK7ACE | |
| SCHEMBL31725783 | 0.84 | KLK5 (0.52) | SCN9ATACR1PPARGKLK7ACE | |
| SCHEMBL16645245 | 0.84 | MAPT (0.61) | SCN9ATACR1PPARGMEN1KMT2A | |
| SCHEMBL17938406 | 0.84 | MAPT (0.61) | SCN9ATACR1PPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843672-B | Preparation method of L-6-hydroxytryptophan derivative and intermediate | 内蒙古大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-117843672-A | Preparation method of L-6-hydroxytryptophan derivative and intermediate | 内蒙古大学 | 2024-04-09 | — | — | CN | disclosed |