Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.66 |
| ▸ | TACR1 | P25103 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.61 |
| ▸ | LTA4H | P09960 | 3/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | KLK7 | P49862 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31407830 | 0.91 | MEN1 (0.73) | SCN9ATACR1MEN1KMT2ATRPM8 | |
| SCHEMBL23929215 | 0.87 | LTA4H (0.62) | SCN9ATACR1MEN1KMT2ATRPM8 | |
| SCHEMBL23929211 | 0.87 | LTA4H (0.62) | SCN9ATACR1MEN1KMT2ATRPM8 | |
| SCHEMBL29186149 | 0.86 | SCN9A (0.63) | SCN9ATACR1MEN1KMT2AKLK7 | |
| SCHEMBL29186151 | 0.86 | SCN9A (0.63) | SCN9ATACR1MEN1KMT2AKLK7 | |
| SCHEMBL23501904 | 0.85 | TACR1 (0.71) | SCN9ATACR1MEN1KMT2AKLK7 | |
| SCHEMBL23501905 | 0.85 | TACR1 (0.71) | SCN9ATACR1MEN1KMT2AKLK7 | |
| SCHEMBL9833617 | 0.85 | CCKBR (0.69) | MEN1KMT2ALTA4HPLA2G2AHSP90AA1 | |
| SCHEMBL1176970 | 0.84 | TACR1 (0.65) | SCN9ATACR1KMT2AKLK7MAPT | |
| SCHEMBL17949554 | 0.83 | TACR1 (0.77) | SCN9ATACR1KLK7MAPTACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881827-B1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2011-09-28 | — | — | EP | disclosed |
| US-7888344-B2 | Fused thiazole derivatives as kinase inhibitors | UCB PHARMA S.A. (BE) | 2011-02-15 | — | — | US | disclosed |
| US-20080306060-A1 | Fused Thiazole Derivatives as Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306060-A1 | Fused Thiazole Derivatives as Kinase Inhibitors | MAP4K2, PDPK1, DAPK2 | SCN9A 2022/4885TACR1 4234/4885MEN1 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.