SCHEMBL2918644

SCHEMBL2918644

Cc1ccc(C=CC(=O)O)cc1[N+](=O)[O-]

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
PLA2G4A P47712 1/20 0.55
ALDH1A1 P00352 8/20 0.54
LMNA P02545 5/20 0.54
HPGD P15428 4/20 0.54
MAPT P10636 8/20 0.50
MAPK1 P28482 5/20 0.50
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
GAA P10253 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HTT P42858 1/20 0.50
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
TDP1 Q9NUW8 4/20 0.49
RECQL P46063 2/20 0.49
KDM4E B2RXH2 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30779749 1.00 TSHR (0.55) TSHRPLA2G4AALDH1A1LMNAHPGD
SCHEMBL2918642 1.00 TSHR (0.55) TSHRPLA2G4AALDH1A1LMNAHPGD
SCHEMBL18023879 0.88 ALDH1A1 (0.54) TSHRALDH1A1LMNAHPGDMAPT
SCHEMBL17978451 0.88 ALDH1A1 (0.54) TSHRALDH1A1LMNAHPGDMAPT
SCHEMBL17978452 0.88 ALDH1A1 (0.54) TSHRALDH1A1LMNAHPGDMAPT
SCHEMBL10492415 0.86 ALDH1A1 (0.53) TSHRPLA2G4AALDH1A1LMNAHPGD
SCHEMBL10492417 0.86 ALDH1A1 (0.53) TSHRPLA2G4AALDH1A1LMNAHPGD
SCHEMBL9779631 0.84 MAPT (0.71) ALDH1A1LMNAHPGDMAPTMAPK1
SCHEMBL9779633 0.84 MAPT (0.71) ALDH1A1LMNAHPGDMAPTMAPK1
SCHEMBL6168986 0.84 ALDH1A1 (0.57) TSHRALDH1A1LMNAHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747059-A1 PERVAPORATION COMPOSITE MEMBRANES McMaster University (CA) 2007-01-31 EP claimed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US claimed
WO-2005102503-A1 PERVAPORATION COMPOSITE MEMBRANES MCMASTER UNIVERSITY (CA) 2005-11-03 WO claimed
EP-2226192-B1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL 1987 LTD (IL) 2016-08-31 EP disclosed
EP-2226116-B1 Drying tube, preparation and use thereof ORIDION MEDICAL 1987 LTD (IL) 2016-04-20 EP disclosed
US-20150283519-A1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL 1987 LTD. (IL) 2015-10-08 US disclosed
US-9090766-B2 Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD. (IL) 2015-07-28 US disclosed
US-9067035-B2 Drying substances, preparation and use thereof ORIDION MEDICAL (1987) LTD. (IL) 2015-06-30 US disclosed
US-20140230652-A1 DRYING SUBSTANCES, PREPARATION AND USE THEREOF ORIDION MEDICAL (1987) LTD. (IL) 2014-08-21 US disclosed
US-8764888-B2 Drying substances, preparation and use thereof ORIDION MEDICAL 1987 LTD. (IL) 2014-07-01 US disclosed
US-8747752-B2 Drying substances, preparation and use thereof ORIDION MEDICAL (1987) LTD. (IL) 2014-06-10 US disclosed
US-20100226824-A1 Drying substances, preparation and use thereof ORIDION MEDICAL (1987) LTD. (IL) 2010-09-09 US disclosed
US-20100224066-A1 Drying substances, preparation and use thereof ORIDION MEDICAL (1987) LTD. (IL) 2010-09-09 US disclosed
EP-2226192-A1 Drying substances, preparation and use thereof Oridion Medical 1987 Ltd. (IL) 2010-09-08 EP disclosed
EP-2226116-A2 Drying substances, preparation and use thereof Oridion Medical 1987 Ltd. (IL) 2010-09-08 EP disclosed
EP-2226341-A2 Drying substances, preparation and use thereof Oridion Medical 1987 Ltd. (IL) 2010-09-08 EP disclosed
US-7604746-B2 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2009-10-20 US disclosed
EP-1747059-A1 PERVAPORATION COMPOSITE MEMBRANES McMaster University (CA) 2007-01-31 EP disclosed
US-20060000778-A1 high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers MCMASTER UNIVERSITY (CA) 2006-01-05 US disclosed
WO-2005102503-A1 PERVAPORATION COMPOSITE MEMBRANES MCMASTER UNIVERSITY (CA) 2005-11-03 WO disclosed