Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR2 | Q16832 | 1/20 | 0.50 |
| ▸ | GAK | O14976 | 3/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.45 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.45 |
| ▸ | STK16 | O75716 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.45 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 7/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30702362 | 1.00 | DDR2 (0.50) | DDR2GAKRIPK2NLKSTK16 | |
| SCHEMBL30702337 | 0.87 | DDR2 (0.64) | DDR2KDRPDGFRACSF1RPDGFRB | |
| SCHEMBL30702360 | 0.87 | DDR2 (0.55) | DDR2RIPK2EGFRKDRPDGFRA | |
| SCHEMBL29186588 | 0.85 | DDR2 (0.53) | DDR2GAKRIPK2NLKKDR | |
| SCHEMBL29186566 | 0.85 | DDR2 (0.53) | DDR2KDRPDGFRACSF1RPDGFRB | |
| SCHEMBL30702339 | 0.85 | DDR2 (0.53) | DDR2GAKRIPK2NLKSTK16 | |
| SCHEMBL30702344 | 0.85 | DDR2 (0.53) | DDR2KDRPDGFRACSF1RPDGFRB | |
| SCHEMBL30702367 | 0.85 | DDR2 (0.53) | DDR2GAKRIPK2NLKKDR | |
| SCHEMBL30702333 | 0.83 | DDR2 (0.50) | DDR2KDRPDGFRAKITABL1 | |
| SCHEMBL30702345 | 0.83 | PDGFRA (0.58) | KDRPDGFRAPDGFRBFGFR2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321036-A | phenyl-O-quinoline, quinazoline, thienopyridine, thienopyrimidine, pyrrolopyridine, pyrrolopyrimidine compounds having anticancer activity | 成都安泰康赛生物科技有限公司 | 2023-12-29 | — | — | CN | disclosed |