Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Azobenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.86 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | DAO | P14920 | 1/20 | 0.70 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azobenzene SCHEMBL27803629 | 1.00 | TRPA1 (0.86) | TRPA1TSHRDAONAPRTALDH1A1 | |
| Azobenzene SCHEMBL27803630 | 1.00 | TRPA1 (0.86) | TRPA1TSHRDAONAPRTALDH1A1 | |
| SCHEMBL168297 | 0.93 | TRPA1 (1.00) | TRPA1TSHRDAONAPRTALDH1A1 | |
| SCHEMBL20307199 | 0.93 | TRPA1 (1.00) | TRPA1TSHRDAONAPRTALDH1A1 | |
| SCHEMBL384410 | 0.93 | TRPA1 (1.00) | TRPA1TSHRDAONAPRTALDH1A1 | |
| SCHEMBL3361521 | 0.93 | TRPA1 (1.00) | TRPA1TSHRDAONAPRTALDH1A1 | |
| Hydrochloric Acid SCHEMBL5067542 | 0.91 | TRPA1 (0.95) | TRPA1TSHRDAONAPRTALDH1A1 | |
| SCHEMBL2229324 | 0.91 | TRPA1 (0.95) | TRPA1TSHRDAONAPRTALDH1A1 | |
| Benzoic Acid SCHEMBL27704901 | 0.89 | TRPA1 (0.77) | TRPA1TSHRDAONAPRTALDH1A1 | |
| Azobenzene SCHEMBL28778962 | 0.89 | TRPA1 (0.69) | TRPA1TSHRDAONAPRTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117700949-A | Low-dielectric halogen-free flame-retardant PBT material, and preparation method and application thereof | 上海中镭新材料科技有限公司 | 2024-03-15 | — | — | CN | claimed |