Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3766762 | 1.00 | PTGS1 (0.49) | PTGS1PTGS2GRIN2BKDM4EALDH1A1 | |
| SCHEMBL3767391 | 0.87 | PTGS1 (0.50) | PTGS1PTGS2GRIN2BALDH1A1PKM | |
| SCHEMBL2920260 | 0.87 | PTGS1 (0.50) | PTGS1PTGS2GRIN2BALDH1A1PKM | |
| SCHEMBL2925552 | 0.83 | PTGS1 (0.52) | PTGS1PTGS2POLBKMT2ASMN1; SMN2 | |
| SCHEMBL3765796 | 0.83 | PTGS1 (0.52) | PTGS1PTGS2POLBKMT2ASMN1; SMN2 | |
| SCHEMBL3769829 | 0.81 | MDM2 (0.40) | PTGS1KDM4EALDH1A1POLBPKM | |
| SCHEMBL3769833 | 0.81 | MDM2 (0.40) | PTGS1KDM4EALDH1A1POLBPKM | |
| SCHEMBL3768883 | 0.80 | PTGS1 (0.41) | PTGS1PTGS2FBP1CES2CES1 | |
| SCHEMBL3768878 | 0.80 | PTGS1 (0.41) | PTGS1PTGS2FBP1CES2CES1 | |
| SCHEMBL2293804 | 0.77 | NPC1 (0.50) | PTGS1PTGS2GRIN2BKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311581-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | BASF SE (DE) | 2010-12-09 | — | — | US | disclosed |
| EP-2224812-A2 | AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009077471-A2 | AZOLYLMETHYLOXIRANES, USE THEREOF AND AGENTS CONTAINING THE SAME | BASF SE (DE) | 2009-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311581-A1 | Azolylmethyloxiranes, use Thereof and Agents Containing the Same | XDH, DAO, DHODH | PTGS1 262/4885PTGS2 369/4885GRIN2B 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.