Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189608 | 1.00 | SLC6A9 (0.32) | SLC6A9CNR2DHODH | |
| SCHEMBL24752118 | 1.00 | SLC6A9 (0.32) | SLC6A9CNR2DHODH | |
| SCHEMBL24752066 | 0.87 | EIF4E (0.33) | — | |
| SCHEMBL24752373 | 0.78 | — | — | |
| SCHEMBL30067166 | 0.78 | JAK2 (0.33) | SLC6A9CNR2DHODH | |
| SCHEMBL24752314 | 0.78 | JAK2 (0.33) | SLC6A9CNR2DHODH | |
| SCHEMBL30067142 | 0.78 | DHODH (0.33) | DHODH | |
| SCHEMBL24752071 | 0.78 | DHODH (0.33) | DHODH | |
| SCHEMBL24752603 | 0.76 | SLC6A9 (0.34) | SLC6A9 | |
| SCHEMBL30067165 | 0.76 | SLC6A9 (0.34) | SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355748-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2024-04-24 | — | — | EP | disclosed |
| CN-117881681-A | Substituted pyrrolo [2,3-d ] pyrimidines, their preparation and their therapeutic use | 赛诺菲 | 2024-04-12 | — | — | CN | disclosed |
| WO-2022263472-A1 | SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-12-22 | — | — | WO | disclosed |