Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 15/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189912 | 1.00 | CD274 (0.39) | CD274PDCD1PDCD1LG2THRBVSIR | |
| SCHEMBL29190054 | 0.92 | CD274 (0.35) | CD274PDCD1PDCD1LG2VSIR | |
| SCHEMBL29190053 | 0.92 | CD274 (0.35) | CD274PDCD1PDCD1LG2VSIR | |
| SCHEMBL29189971 | 0.91 | CD274 (0.34) | CD274PDCD1PDCD1LG2VSIR | |
| SCHEMBL29189974 | 0.91 | CD274 (0.34) | CD274PDCD1PDCD1LG2VSIR | |
| SCHEMBL29190137 | 0.91 | KCNH2 (0.39) | CD274PDCD1KDM4EALDH1A1 | |
| SCHEMBL29190045 | 0.90 | CD274 (0.34) | CD274PDCD1PDCD1LG2VSIR | |
| SCHEMBL29190040 | 0.90 | CD274 (0.34) | CD274PDCD1PDCD1LG2VSIR | |
| SCHEMBL29189879 | 0.90 | CD274 (0.34) | CD274PDCD1PDCD1LG2VSIR | |
| SCHEMBL29189877 | 0.90 | CD274 (0.34) | CD274PDCD1PDCD1LG2VSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |