Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189912 | 0.91 | CD274 (0.39) | CD274KDM4EALDH1A1PDCD1 | |
| SCHEMBL29189910 | 0.91 | CD274 (0.39) | CD274KDM4EALDH1A1PDCD1 | |
| SCHEMBL29189973 | 0.91 | CD274 (0.37) | KCNH2CYP2D6GRIN2BCD274KDM4E | |
| SCHEMBL29189955 | 0.90 | MDM2 (0.31) | CD274RPS6KA2PDCD1 | |
| SCHEMBL29189954 | 0.90 | MDM2 (0.31) | CD274RPS6KA2PDCD1 | |
| SCHEMBL29189956 | 0.89 | KCNH2 (0.37) | KCNH2CD274KDM4EGAAALDH1A1 | |
| SCHEMBL29189886 | 0.89 | KCNH2 (0.36) | KCNH2CYP2D6GRIN2BCD274DRD2 | |
| SCHEMBL29190133 | 0.89 | VSIR (0.35) | KCNH2CD274DRD2DRD4DRD3 | |
| SCHEMBL29189982 | 0.87 | S1PR1 (0.35) | KCNH2CD274PDCD1 | |
| SCHEMBL29190061 | 0.87 | MAPT (0.39) | KDM4EKMT2AGAAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |