Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 9/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
| ▸ | CBLB | Q13191 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 2/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29189916 | 0.97 | S1PR1 (0.35) | S1PR1S1PR3CD274PDCD1CBLB | |
| SCHEMBL29190092 | 0.91 | CD274 (0.35) | S1PR1S1PR3CD274PDCD1 | |
| SCHEMBL29190090 | 0.91 | CD274 (0.35) | S1PR1S1PR3CD274PDCD1 | |
| SCHEMBL29189986 | 0.91 | S1PR1 (0.36) | S1PR1S1PR3CD274PDCD1CBLB | |
| SCHEMBL29189931 | 0.89 | VSIR (0.36) | S1PR1S1PR3CD274PDCD1CBLB | |
| SCHEMBL29189949 | 0.89 | S1PR1 (0.36) | S1PR1S1PR3CD274PDCD1CBLB | |
| SCHEMBL29190104 | 0.89 | S1PR1 (0.36) | S1PR1S1PR3CD274PDCD1CBLB | |
| SCHEMBL29190109 | 0.89 | MDM2 (0.34) | S1PR1S1PR3CBLB | |
| SCHEMBL29190106 | 0.89 | MDM2 (0.34) | S1PR1S1PR3CBLB | |
| SCHEMBL29190103 | 0.88 | S1PR1 (0.33) | S1PR1S1PR3CD274PDCD1CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |