SCHEMBL291900

SCHEMBL291900

CCOC(=O)c1cc(-c2cccc3ccccc23)c(C(=O)OCC)cc1-c1cccc2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 4/20 0.62
CDC25A P30304 1/20 0.58
CDC25C P30307 1/20 0.58
TSHR P16473 1/20 0.54
KDM4E B2RXH2 4/20 0.53
ALDH1A1 P00352 4/20 0.53
GLA P06280 1/20 0.53
GAA P10253 1/20 0.53
FNTA P49354 1/20 0.53
FNTB P49356 1/20 0.53
KMT2A Q03164 4/20 0.50
MAPK1 P28482 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CNR2 P34972 1/20 0.49
MEN1 O00255 2/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
HPGD P15428 1/20 0.49
TDP1 Q9NUW8 1/20 0.48
CCR6 P51684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20806378 0.92 CDC25B (0.54) CDC25BCDC25ACDC25CTSHRKDM4E
SCHEMBL1760245 0.92 CDC25B (0.54) CDC25BCDC25ACDC25CTSHRKDM4E
SCHEMBL1560864 0.92 CDC25B (0.54) CDC25BCDC25ACDC25CTSHRKDM4E
SCHEMBL1560874 0.90 CDC25B (0.52) CDC25BCDC25ACDC25CTSHRKDM4E
SCHEMBL4072424 0.89 CDC25B (0.68) CDC25BCDC25ACDC25CTSHRKDM4E
SCHEMBL10299009 0.89 CDC25B (0.51) CDC25BCDC25ACDC25CTSHRKDM4E
SCHEMBL20806419 0.89 CDC25B (0.51) CDC25BCDC25ACDC25CTSHRKDM4E
SCHEMBL18428555 0.88 CDC25B (0.67) CDC25BCDC25ACDC25CTSHRKDM4E
SCHEMBL17836985 0.86 CDC25B (0.54) CDC25BCDC25ACDC25CTSHRKDM4E
SCHEMBL10299011 0.86 CDC25B (0.51) CDC25BCDC25ACDC25CTSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9175132-B2 Polymers comprising structural units which contain alkylalkoxy groups, blends comprising these polymers, and opto-electronic devices comprising these polymers and blends MERCK PATENT GMBH (DE) 2015-11-03 US disclosed
US-9175132-B2 Polymers comprising structural units which contain alkylalkoxy groups, blends comprising these polymers, and opto-electronic devices comprising these polymers and blends MERCK PATENT GMBH (DE) 2015-11-03 US disclosed
US-8932732-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-01-13 US disclosed
US-8932732-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-01-13 US disclosed
US-8932732-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-01-13 US disclosed
US-20120097938-A1 POLYMERS COMPRISING STRUCTURAL UNITS WHICH CONTAIN ALKYLALKOXY GROUPS, BLENDS COMPRISING THESE POLYMERS, AND OPTO-ELECTRONIC DEVICES COMPRISING THESE POLYMERS AND BLENDS MERCK PATENT GMBH (DE) 2012-04-26 US disclosed
US-20120097938-A1 POLYMERS COMPRISING STRUCTURAL UNITS WHICH CONTAIN ALKYLALKOXY GROUPS, BLENDS COMPRISING THESE POLYMERS, AND OPTO-ELECTRONIC DEVICES COMPRISING THESE POLYMERS AND BLENDS MERCK PATENT GMBH (DE) 2012-04-26 US disclosed
EP-2024310-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-03-14 EP disclosed
EP-2024310-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-03-14 EP disclosed
US-20090184313-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2009-07-23 US disclosed
US-20090184313-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2009-07-23 US disclosed
US-20090184313-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2009-07-23 US disclosed
EP-2024310-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2009-02-18 EP disclosed
WO-2007140847-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2007-12-13 WO disclosed
WO-2007140847-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2007-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090184313-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2A1, SLCO1A2 CDC25B 4083/4885CDC25A 4223/4885CDC25C 4275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.