SCHEMBL4072424

SCHEMBL4072424

CCOC(=O)c1ccccc1-c1cccc2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 5/20 0.68
CDC25A P30304 1/20 0.63
CDC25C P30307 1/20 0.63
TSHR P16473 1/20 0.61
ALDH1A1 P00352 4/20 0.56
KDM4E B2RXH2 2/20 0.56
FNTA P49354 1/20 0.54
FNTB P49356 1/20 0.54
HSD17B10 Q99714 1/20 0.53
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
USP2 O75604 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
CYP2C9 P11712 1/20 0.52
ALOX15 P16050 1/20 0.52
CYP2C19 P33261 1/20 0.52
MAPK10 P53779 1/20 0.52
PTK2B Q14289 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18428555 0.98 CDC25B (0.67) CDC25BCDC25ACDC25CTSHRALDH1A1
SCHEMBL291900 0.89 CDC25B (0.62) CDC25BCDC25ACDC25CTSHRALDH1A1
SCHEMBL277672 0.87 CDC25B (0.82) CDC25BCDC25ACDC25CTSHRALDH1A1
SCHEMBL17614211 0.87 CDC25B (0.56) CDC25BCDC25ACDC25CTSHRALDH1A1
SCHEMBL29617021 0.87 TSHR (0.80) CDC25BCDC25ACDC25CTSHRALDH1A1
SCHEMBL3683272 0.87 TSHR (0.80) CDC25BCDC25ACDC25CTSHRALDH1A1
SCHEMBL2129231 0.86 CDC25B (0.62) CDC25BCDC25ACDC25CTSHRALDH1A1
SCHEMBL6598620 0.85 CDC25B (0.58) CDC25BCDC25ACDC25CTSHRALDH1A1
SCHEMBL31083364 0.85 FNTA (0.55) CDC25BCDC25ACDC25CTSHRALDH1A1
SCHEMBL17836985 0.85 CDC25B (0.54) CDC25BCDC25ACDC25CTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439146-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-10-08 US disclosed
US-20170040535-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-02-09 US disclosed
US-20170040535-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-02-09 US disclosed
EP-2006278-B2 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORP (JP) 2016-10-12 EP disclosed
CN-102643161-B Benzofluorene compound and uses thereof TOSOH CORPORATION (JP) 2015-10-14 CN disclosed
CN-104768940-A organic electroluminescent element IDEMITSU KOSAN CO 2015-07-08 CN disclosed
US-8993805-B2 Benzofluorene compound and use thereof TOSOH CORPORATION (JP) 2015-03-31 US disclosed
US-8993805-B2 Benzofluorene compound and use thereof TOSOH CORPORATION (JP) 2015-03-31 US disclosed
US-8993805-B2 Benzofluorene compound and use thereof TOSOH CORPORATION (JP) 2015-03-31 US disclosed
CN-101421226-B Benzofluorene compound and use thereof TOSOH CORP 2013-05-22 CN disclosed
EP-2006278-B1 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORP (JP) 2012-12-26 EP disclosed
CN-102643161-A Benzofluorene compound and use thereof TOSOH CORP 2012-08-22 CN disclosed
EP-2006278-A9 BENZOFLUORENE COMPOUND AND USE THEREOF Tosoh Corporation (JP) 2009-08-05 EP disclosed
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2009-07-23 US disclosed
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2009-07-23 US disclosed
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2009-07-23 US disclosed
CN-101421226-A Benzofluorene compound and use thereof TOSOH CORP (JP) 2009-04-29 CN disclosed
EP-2006278-A2 BENZOFLUORENE COMPOUND AND USE THEREOF Tosoh Corporation (JP) 2008-12-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170040535-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SUN2, OCIAD1, OCIAD2 CDC25B 4711/4885CDC25A 4637/4885CDC25C 4808/4885
US-20090184312-A1 BENZOFLUORENE COMPOUND AND USE THEREOF SLC7A1, SLC43A1, SLC7A5 CDC25B 4176/4885CDC25A 4002/4885CDC25C 4482/4885
US-10439146-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SUN2, OCIAD1, OCIAD2 CDC25B 4711/4885CDC25A 4637/4885CDC25C 4808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.