Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 9/20 | 0.39 |
| ▸ | VSIR | Q9H7M9 | 9/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190051 | 0.89 | CD274 (0.32) | CD274PDCD1VSIRPDCD1LG2 | |
| SCHEMBL29190068 | 0.88 | CD274 (0.36) | CD274PDCD1VSIR | |
| SCHEMBL29190012 | 0.88 | VSIR (0.39) | CD274PDCD1VSIR | |
| SCHEMBL29190002 | 0.88 | VSIR (0.39) | CD274PDCD1VSIR | |
| SCHEMBL29189911 | 0.86 | VSIR (0.38) | CD274PDCD1VSIR | |
| SCHEMBL29189980 | 0.86 | VSIR (0.34) | CD274PDCD1VSIRPDCD1LG2 | |
| SCHEMBL29190034 | 0.85 | VSIR (0.34) | CD274PDCD1VSIR | |
| SCHEMBL29190110 | 0.85 | IDO1 (0.36) | CD274PDCD1VSIR | |
| SCHEMBL29189992 | 0.85 | VSIR (0.37) | CD274PDCD1VSIR | |
| SCHEMBL29189934 | 0.84 | VSIR (0.38) | CD274PDCD1VSIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |