Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31430607 | 1.00 | HPGD (0.48) | HPGDMEN1KMT2ARXFP1ESR1 | |
| SCHEMBL5470372 | 0.93 | HPGD (0.54) | HPGDMEN1KMT2ARXFP1ESR1 | |
| SCHEMBL22689342 | 0.85 | HPGD (0.47) | HPGDMEN1KMT2AVCAM1KDM4E | |
| SCHEMBL5924211 | 0.83 | ESR1 (0.57) | MEN1KMT2ARXFP1ESR1ERN1 | |
| SCHEMBL22696475 | 0.83 | HPGD (0.44) | HPGDMEN1KMT2AVCAM1KDM4E | |
| Hydrochloric Acid SCHEMBL9064842 | 0.82 | ESR1 (0.56) | MEN1KMT2ARXFP1ESR1ERN1 | |
| SCHEMBL11965650 | 0.82 | HPGD (0.58) | HPGDMEN1KMT2AVCAM1MAPT | |
| SCHEMBL28679664 | 0.81 | HPGD (0.44) | HPGDMEN1KMT2AVCAM1KDM4E | |
| SCHEMBL14581924 | 0.80 | HPGD (0.54) | HPGDMEN1KMT2AVCAM1KDM4E | |
| SCHEMBL643856 | 0.79 | KDM4E (0.65) | HPGDMEN1KMT2ARXFP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |