Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31430607 | 0.93 | HPGD (0.48) | HPGDALDH1A1OPRK1MEN1KMT2A | |
| SCHEMBL29190026 | 0.93 | HPGD (0.48) | HPGDALDH1A1OPRK1MEN1KMT2A | |
| SCHEMBL14581924 | 0.87 | HPGD (0.54) | HPGDALDH1A1OPRK1MEN1KMT2A | |
| SCHEMBL14612869 | 0.84 | HPGD (0.51) | HPGDALDH1A1OPRK1MEN1KMT2A | |
| SCHEMBL3901403 | 0.83 | HPGD (0.65) | HPGDALDH1A1OPRK1MEN1KMT2A | |
| SCHEMBL5924211 | 0.80 | ESR1 (0.57) | MEN1KMT2ARXFP1ESR1ERN1 | |
| SCHEMBL22689342 | 0.79 | HPGD (0.47) | HPGDALDH1A1OPRK1MEN1KMT2A | |
| SCHEMBL12488269 | 0.79 | HPGD (0.59) | HPGDALDH1A1MEN1KMT2AERN1 | |
| Hydrochloric Acid SCHEMBL9064842 | 0.79 | ESR1 (0.56) | MEN1KMT2ARXFP1ESR1ERN1 | |
| SCHEMBL5303674 | 0.79 | KDM4E (0.44) | HPGDALDH1A1MEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032488-A1 | 6-Membered aryl and heteroaryl derivatives for treating viruses | GENELABS TECHNOLOGIES, INC. | 2007-02-08 | — | — | US | disclosed |
| US-20070032488-A1 | 6-Membered aryl and heteroaryl derivatives for treating viruses | GENELABS TECHNOLOGIES, INC. | 2007-02-08 | — | — | US | disclosed |
| US-20070032488-A1 | 6-Membered aryl and heteroaryl derivatives for treating viruses | GENELABS TECHNOLOGIES, INC. | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032488-A1 | 6-Membered aryl and heteroaryl derivatives for treating viruses | HAVCR2, MAVS, EIF2AK2 | HPGD 4171/4885ALDH1A1 1740/4885OPRK1 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.