Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24735127 | 0.97 | CRBN (0.47) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL30158207 | 0.97 | CRBN (0.47) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL30612355 | 0.94 | MEN1 (0.51) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL24735228 | 0.94 | MEN1 (0.51) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL30148829 | 0.92 | CRBN (0.42) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL21409182 | 0.89 | KMT2A (0.50) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL25941790 | 0.89 | CRBN (0.47) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL30009045 | 0.89 | PDE4B (0.47) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL21409304 | 0.89 | PDE4B (0.47) | CRBNNR3C1PGRSLC6A4KCNH2 | |
| SCHEMBL30278930 | 0.88 | PDE4A (0.45) | CRBNNR3C1PGRSLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936498-B | N- (3- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) phenyl) benzamide derivatives | 诺华股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-111936498-A | N- (3- (7H-pyrrolo [2,3-d ] pyrimidin-4-yl) phenyl) benzamide derivatives | 诺华股份有限公司 | 2020-11-13 | — | — | CN | disclosed |