SCHEMBL29192511

SCHEMBL29192511

CCCCCCCCOC(=O)CCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C(=O)OCCCCCCCC

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.41
ESR1 P03372 3/20 0.39
AKR1C4 P17516 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
CNR2 P34972 2/20 0.39
GAA P10253 2/20 0.39
KMT2A Q03164 1/20 0.39
HTR2C P28335 1/20 0.38
XBP1 P17861 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
NAAA Q02083 1/20 0.38
DGKA P23743 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22749431 0.92 HMGCR (0.45) HMGCRESR1AKR1C4AKR1C3AKR1C2
SCHEMBL18040863 0.92 HMGCR (0.45) HMGCRESR1AKR1C4AKR1C3AKR1C2
SCHEMBL3938564 0.90 HMGCR (0.40) HMGCRCNR2GAAKMT2AATM
SCHEMBL3350955 0.87 HMGCR (0.45) HMGCRESR1AKR1C4AKR1C3AKR1C2
SCHEMBL10433646 0.87 HMGCR (0.45) HMGCRESR1AKR1C4AKR1C3AKR1C2
SCHEMBL5076172 0.85 PTGES (0.45) HMGCRCNR2GAAKMT2ADGKA
SCHEMBL30982225 0.85 PTGES (0.45) HMGCRCNR2GAAKMT2ADGKA
SCHEMBL11413683 0.83 PPARG (0.41) HMGCRESR1AKR1C4AKR1C3AKR1C2
SCHEMBL581163 0.82 HMGCR (0.45) HMGCRESR1AKR1C4AKR1C3AKR1C2
SCHEMBL870709 0.82 HMGCR (0.45) HMGCRESR1AKR1C4AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117561319-A O-alkylated sterically hindered antioxidants 松原实业有限公司 2024-02-13 CN disclosed