SCHEMBL29196008

SCHEMBL29196008

FC(F)(F)c1cccc2c1oc1cc[c]cc12

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
CYP2C19 P33261 1/20 0.36
KMT2A Q03164 1/20 0.36
CDC14B O60729 3/20 0.34
CDC14A Q9UNH5 3/20 0.34
EPHX2 P34913 3/20 0.33
KIF11 P52732 1/20 0.32
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HSD17B10 Q99714 1/20 0.30
HPGD P15428 1/20 0.30
PPARG P37231 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
NCOR2 Q9Y618 1/20 0.30
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP1B1 Q16678 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27212349 0.88 MEN1 (0.36) MEN1CYP2C19KMT2ACDC14BCDC14A
SCHEMBL28264661 0.80 CYP2C19 (0.51) MEN1CYP2C19KMT2ACDC14BCDC14A
SCHEMBL25906220 0.77 EPHX2 (0.42) MEN1CYP2C19KMT2ACDC14BCDC14A
SCHEMBL2957443 0.76 AHR (0.50) MEN1KMT2ASMN1; SMN2CYP1A2
SCHEMBL21296139 0.76 MCL1 (0.39) MEN1KMT2AKDM4ERXFP1CYP1A2
SCHEMBL21295800 0.72 ALOX5 (0.46) MEN1CYP2C19KMT2ACDC14BCDC14A
SCHEMBL16273157 0.72 CYP1A1 (0.41) MEN1CYP2C19KMT2AKDM4ESMN1; SMN2
SCHEMBL27212345 0.71 EPHX2 (0.35) MEN1KMT2AEPHX2KIF11KDM4E
SCHEMBL26072015 0.71 KMT2A (0.41) CYP2C19KMT2AKDM4ESMN1; SMN2HSD17B10
SCHEMBL5133924 0.71 KDM4E (0.33) KDM4ESMN1; SMN2HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN disclosed