Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31076166 | 0.89 | MEN1 (0.42) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| Iodide SCHEMBL28851041 | 0.85 | MEN1 (0.46) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| Bromide SCHEMBL11517500 | 0.83 | MEN1 (0.49) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| Bromide SCHEMBL5214341 | 0.83 | MEN1 (0.49) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| Bromide SCHEMBL3662825 | 0.82 | MEN1 (0.51) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| Bromide SCHEMBL11354372 | 0.82 | MEN1 (0.51) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| Bromide SCHEMBL31076183 | 0.82 | MEN1 (0.51) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| Bromide SCHEMBL8442020 | 0.82 | MEN1 (0.51) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| Iodide SCHEMBL7755123 | 0.80 | MEN1 (0.49) | MEN1KMT2AKDM4CL3MBTL1NPC1 | |
| Bromide SCHEMBL7324390 | 0.80 | KDM4C (0.47) | MEN1KMT2AKDM4CL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924017-A | Organic halogen compound having conjugated double bond, method for preparing acetate and alcohol derivative thereof, and compound for synthesizing the compound | 信越化学工业株式会社 | 2024-04-26 | — | — | CN | disclosed |