Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23272135 | 0.79 | DPP4 (0.55) | DPP4DPP8L3MBTL1DPP7TSHR | |
| SCHEMBL29196914 | 0.79 | DPP4 (0.55) | DPP4DPP8L3MBTL1DPP7TSHR | |
| SCHEMBL29196918 | 0.76 | DPP4 (0.87) | DPP4DPP8DPP7 | |
| SCHEMBL29196904 | 0.76 | DPP4 (0.36) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL29196926 | 0.76 | DPP4 (0.36) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL29196920 | 0.76 | DPP4 (0.87) | DPP4DPP8DPP7 | |
| SCHEMBL29196905 | 0.72 | DPP4 (0.63) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL29196907 | 0.72 | DPP4 (0.63) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL14919832 | 0.70 | DPP4 (0.66) | DPP4DPP8DPP7 | |
| SCHEMBL12233461 | 0.66 | TSHR (0.63) | DPP4DPP8L3MBTL1TSHRHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720540-A | Sitagliptin intermediate and preparation method of sitagliptin | 宜昌东阳光制药有限公司 | 2024-03-19 | — | — | CN | disclosed |