Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29196926 | 1.00 | DPP4 (0.36) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL29196899 | 0.76 | DPP4 (0.54) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL29197294 | 0.73 | DPP4 (0.45) | DPP4DPP8DPP7 | |
| SCHEMBL29196896 | 0.69 | DPP4 (0.40) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL14919832 | 0.64 | DPP4 (0.66) | DPP4DPP8DPP7 | |
| SCHEMBL21565165 | 0.59 | DPP4 (0.53) | DPP4DPP8DPP7 | |
| SCHEMBL21985109 | 0.57 | DPP4 (0.88) | DPP4DPP8DPP7 | |
| SCHEMBL21985110 | 0.57 | DPP4 (0.88) | DPP4DPP8DPP7 | |
| SCHEMBL23272135 | 0.56 | DPP4 (0.55) | DPP4DPP8DPP7 | |
| SCHEMBL14920043 | 0.55 | DPP4 (0.39) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720540-A | Sitagliptin intermediate and preparation method of sitagliptin | 宜昌东阳光制药有限公司 | 2024-03-19 | — | — | CN | disclosed |